New Organometallic Ru(II) Compounds with Lonidamine Motif as Antitumor Agents

• Main Authors: Ilya A. Shutkov (Author), Yulia N. Okulova (Author), Dmitrii M. Mazur (Author), Nikolai A. Melnichuk (Author), Denis A. Babkov (Author), Elena V. Sokolova (Author), Alexander A. Spasov (Author), Elena R. Milaeva (Author), Alexey A. Nazarov (Author)
• Format: Knjiga
• Izdano: MDPI AG, 2023-04-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

The combination of one molecule of organic and metal-based fragments that exhibit antitumor activity is a modern approach in the search for new promising drugs. In this work, biologically active ligands based on lonidamine (a selective inhibitor of aerobic glycolysis used in clinical practice) were...