Pharmacokinetic assessment of vancomycin in critically ill patients and nephrotoxicity prediction using individualized pharmacokinetic parameters

• Main Authors: Parisa Ghasemiyeh (Author), Afsaneh Vazin (Author), Farid Zand (Author), Elham Haem (Author), Iman Karimzadeh (Author), Amir Azadi (Author), Mansoor Masjedi (Author), Golnar Sabetian (Author), Reza Nikandish (Author), Soliman Mohammadi-Samani (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Therapeutic drug monitoring (TDM) and pharmacokinetic assessments of vancomycin would be essential to avoid vancomycin-associated nephrotoxicity and obtain optimal therapeutic and clinical responses. Different pharmacokinetic parameters, including trough concentration and area under th...