Feasibility and safety of research sigmoid colon biopsy in a cohort of Thai men who have sex with men with acute HIV-1

• Main Authors: Michelle Chintanaphol (Author), Carlo Sacdalan (Author), Suteeraporn Pinyakorn (Author), Rungsun Rerknimitr (Author), Wiriyaporn Ridtitid (Author), Piyapan Prueksapanich (Author), Irini Sereti (Author), Alexandra Schuetz (Author), Trevor A. Crowell (Author), Donn J. Colby (Author), Merlin L. Robb (Author), Nittaya Phanuphak (Author), Jintanat Ananworanich (Author), Serena S. Spudich (Author), Eugène Kroon (Author)
• Format: Book
• Published: Elsevier, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: The gut-associated lymphoid tissue (GALT) is a major reservoir of HIV-1 established early in acute HIV-1 infection (AHI). Sampling tissue from GALT can provide information about viral reservoirs and immune responses but may be complicated during AHI for reasons such as high viral replica...