Celastrol Suppresses Glioma Vasculogenic Mimicry Formation and Angiogenesis by Blocking the PI3K/Akt/mTOR Signaling Pathway

• Váldodahkkit: Yingjun Zhu (Dahkki), Xihong Liu (Dahkki), Peiyuan Zhao (Dahkki), Hui Zhao (Dahkki), Wei Gao (Dahkki), Lei Wang (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Frontiers Media S.A., 2020-02-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Angiogenesis and vasculogenic mimicry (VM) are thought to be the predominant processes ensuring tumor blood supply during the growth and metastasis of glioblastoma (GBM). Celastrol has potential anti-glioma effects, however the mechanisms underlying these effects remain unclarified. Recent studies h...