Improvement of Biocatalytic Properties and Cytotoxic Activity of L-Asparaginase from <i>Rhodospirillum rubrum</i> by Conjugation with Chitosan-Based Cationic Polyelectrolytes

• Главные авторы: Natalia V. Dobryakova (Автор), Dmitry D. Zhdanov (Автор), Nikolay N. Sokolov (Автор), Svetlana S. Aleksandrova (Автор), Marina V. Pokrovskaya (Автор), Elena V. Kudryashova (Автор)
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• Опубликовано: MDPI AG, 2022-03-01T00:00:00Z.
• Предметы: article
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L-asparaginases (L-ASNases, EC 3.5.1.1) are a family of enzymes that are widely used for the treatment of lymphoblastic leukemias. L-ASNase from <i>Rhodospirillum rubrum</i> (RrA) has a low molecular weight, low glutaminase activity, and low immunogenicity, making it a promising enzyme f...