Inhibiting <i>Leishmania donovani</i> Sterol Methyltransferase to Identify Lead Compounds Using Molecular Modelling

• Main Authors: Patrick O. Sakyi (Author), Samuel K. Kwofie (Author), Julius K. Tuekpe (Author), Theresa M. Gwira (Author), Emmanuel Broni (Author), Whelton A. Miller (Author), Michael D. Wilson (Author), Richard K. Amewu (Author)
• Format: Book
• Published: MDPI AG, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The recent outlook of leishmaniasis as a global public health concern coupled with the reportage of resistance and lack of efficacy of most antileishmanial drugs calls for a concerted effort to find new leads. The study combined <i>In silico</i> and in vitro approaches to identify novel...