Programmed Catalytic Therapy-Mediated ROS Generation and T-Cell Infiltration in Lung Metastasis by a Dual Metal-Organic Framework (MOF) Nanoagent

• Main Authors: Bhanu Nirosha Yalamandala (Author), Pin-Hua Chen (Author), Thrinayan Moorthy (Author), Thi My Hue Huynh (Author), Wen-Hsuan Chiang (Author), Shang-Hsiu Hu (Author)
• Format: Book
• Published: MDPI AG, 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nano-catalytic agents actuating Fenton-like reaction in cancer cells cause intratumoral generation of reactive oxygen species (ROS), allowing the potential for immune therapy of tumor metastasis via the recognition of tumor-associated antigens. However, the self-defense mechanism of cancer cells, kn...