The Physiology, Pathology, and Therapeutic Interventions for ROCK Isoforms in Diabetic Kidney Disease

• Main Authors: Keiichiro Matoba (Author), Yusuke Takeda (Author), Yosuke Nagai (Author), Kensuke Sekiguchi (Author), Tamotsu Yokota (Author), Kazunori Utsunomiya (Author), Rimei Nishimura (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Rho-associated coiled-coil-containing protein kinase (ROCK) is a serine/threonine kinase that was originally identified as RhoA interacting protein. A diverse array of cellular functions, including migration, proliferation, and phenotypic modulation, are orchestrated by ROCK through a mechanism invo...