Regulation of p27 (Kip1) by Ubiquitin E3 Ligase RNF6
The cyclin-dependent kinase inhibitor p27 (Kip1) is an important regulator of the G1/S checkpoint. It is degraded by the SCF-SKP2 complex in late G1 thereby allowing cells to progress to the S phase. Here we investigated the role of the E3 ubiquitin ligase RNF6 (Ring Finger Protein 6) in cell cycle...
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Main Authors: | , , , , , |
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Format: | Book |
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MDPI AG,
2022-04-01T00:00:00Z.
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A1234.567 |
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Copy 1 | Available |