NTRK Fusions in a Sarcomas Series: Pathology, Molecular and Clinical Aspects

• Main Authors: Vasiliki Siozopoulou (Author), Elly Marcq (Author), Koen De Winne (Author), Koen Norga (Author), Gertjan Schmitz (Author), Valerie Duwel (Author), Philippe Delvenne (Author), Evelien Smits (Author), Patrick Pauwels (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Targeting molecular alterations has been proven to be an inflecting point in tumor treatment. Especially in recent years, inhibitors that target the tyrosine receptor kinase show excellent response rates and durable effects in all kind of tumors that harbor fusions of one of the three neurotrophic t...