Multicomponent Lipid Nanoparticles for RNA Transfection

• Main Authors: Nataliya Gretskaya (Author), Mikhail Akimov (Author), Dmitry Andreev (Author), Anton Zalygin (Author), Ekaterina Belitskaya (Author), Galina Zinchenko (Author), Elena Fomina-Ageeva (Author), Ilya Mikhalyov (Author), Elena Vodovozova (Author), Vladimir Bezuglov (Author)
• Format: Book
• Published: MDPI AG, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Despite the wide variety of available cationic lipid platforms for the delivery of nucleic acids into cells, the optimization of their composition has not lost its relevance. The purpose of this work was to develop multi-component cationic lipid nanoparticles (LNPs) with or without a hydrophobic cor...