Sweet Cherry Extract as Permeation Enhancer of Tyrosine Kinase Inhibitors: A Promising Prospective for Future Oral Anticancer Therapies

• Main Authors: Federica Poggialini (Author), Chiara Vagaggini (Author), Annalaura Brai (Author), Claudia Pasqualini (Author), Anna Carbone (Author), Francesca Musumeci (Author), Silvia Schenone (Author), Elena Dreassi (Author)
• Format: Book
• Published: MDPI AG, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Although patients would rather oral therapies to injections, the gastrointestinal tract's low permeability makes this method limiting for most compounds, including anticancer drugs. Due to their low bioavailability, oral antitumor therapies suffer from significant variability in pharmacokinetic...