High tumor mutation burden is associated with DNA damage repair gene mutation in breast carcinomas

Abstract Background Immunotherapy has demonstrated encouraging clinical benefits in patients with advanced breast carcinomas and Programmed death ligand 1 (PD-L1) expression has been proposed as an immunotherapy biomarker. Challenges with current PD-L1 testing exist and tumor mutation burden (TMB) i...

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Bibliographic Details
Main Authors: Ping Mei (Author), C. Eric Freitag (Author), Lai Wei (Author), Yunxiang Zhang (Author), Anil V. Parwani (Author), Zaibo Li (Author)
Format: Book
Published: BMC, 2020-05-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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