High tumor mutation burden is associated with DNA damage repair gene mutation in breast carcinomas
Abstract Background Immunotherapy has demonstrated encouraging clinical benefits in patients with advanced breast carcinomas and Programmed death ligand 1 (PD-L1) expression has been proposed as an immunotherapy biomarker. Challenges with current PD-L1 testing exist and tumor mutation burden (TMB) i...
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BMC,
2020-05-01T00:00:00Z.
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