Acacetin inhibits invasion, migration and TGF-β1-induced EMT of gastric cancer cells through the PI3K/Akt/Snail pathway

• Main Authors: Guangtao Zhang (Author), Zhaoyan Li (Author), Jiahuan Dong (Author), Weili Zhou (Author), Zhanxia Zhang (Author), Zujun Que (Author), Xiaohong Zhu (Author), Yan Xu (Author), Nida Cao (Author), Aiguang Zhao (Author)
• Format: Book
• Published: BMC, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Epithelial-to-mesenchymal transition (EMT) is a pivotal cellular phenomenon involved in tumour metastasis and progression. In gastric cancer (GC), EMT is the main reason for recurrence and metastasis in postoperative patients. Acacetin exhibits various biological activities. Howe...