Sequential magnetic resonance spectroscopic changes in a patient with nonketotic hyperglycinemia

• Main Authors: Ji Hun Shin (Author), So Yoon Ahn (Author), Jeong Hee Shin (Author), Se In Sung (Author), Ji Mi Jung (Author), Jin Kyu Kim (Author), Eun Sun Kim (Author), Hyung Doo Park (Author), Ji Hye Kim (Author), Yun Sil Chang (Author), Won Soon Park (Author)
• Format: Book
• Published: Korean Pediatric Society, 2012-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nonketotic hyperglycinemia (NKH) is a rare inborn error of amino acid metabolism. A defect in the glycine cleavage enzyme system results in highly elevated concentrations of glycine in the plasma, urine, cerebrospinal fluid, and brain, resulting in glycine-induced encephalopathy and neuropathy. The...