Evidence for Arrhythmogenic Effects of A2A-Adenosine Receptors

• Main Authors: Peter Boknik (Author), Katharina Drzewiecki (Author), John Eskandar (Author), Ulrich Gergs (Author), Britt Hofmann (Author), Hendrik Treede (Author), Stephanie Grote-Wessels (Author), Larissa Fabritz (Author), Paulus Kirchhof (Author), Lisa Fortmüller (Author), Frank Ulrich Müller (Author), Wilhelm Schmitz (Author), Norbert Zimmermann (Author), Uwe Kirchhefer (Author), Joachim Neumann (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Adenosine can be released from the heart and may stimulate four different cardiac adenosine receptors. A receptor subtype that couples to the generation of cyclic adenosine monophosphate (cAMP) is the A2A-adenosine receptor (A2A-AR). To better understand its role in cardiac function, we studied mech...