Cardiac Complications Caused by Respiratory Syncytial Virus Infection: Questionnaire Survey and a Literature Review

• Main Authors: Hisashi Kawashima MD, PhD (Author), Natsuko Inagaki MD, PhD (Author), Toshihiro Nakayama MD (Author), Shinichiro Morichi MD, PhD (Author), Shigeo Nishimata MD, PhD (Author), Gaku Yamanaka MD, PhD (Author), Yasuyo Kashiwagi MD, PhD (Author)
• Format: Book
• Published: SAGE Publishing, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.
• Notes: 2333-794X; 10.1177/2333794X211044114
• Keywords: Pediatrics; RJ1-570
• Source: Global Pediatric Health, Vol 8 (2021)

We investigated 22 cases of patients with myocarditis during respiratory syncytial virus (RSV) infection by a questionnaire survey, and performed a literature search to clarify their characteristics. The age distribution was divided into 2 groups, that is, 1 group comprised of patients younger than 4-years old and the other comprised patients older than 15 years. ECG demonstrated disturbance of the conduction system (AV block) in 7 out of 18 patients (38.8%), myocardial damage (ST-T change) in 9 out of 18 patients (50.0%), and tachycardia in 3 out of 18 patients (16.6%). Echocardiography displayed a robust decrease in left-heart function in 12 out of 14 patients. The outcome was 2 deaths, 1 pacemaker placement, 4 patients with mild sequel. Our data suggest that RSV myocarditis caused by RSV infection can be divided into 3 different pathophysiologies, characterized by disturbance of the conduction system, myocardial damage, and increase of autonomy.