Doxorubicin-loaded zein in situ gel for interstitial chemotherapy of colorectal cancer

• Main Authors: Ning Shen (Author), Jie Hu (Author), Linan Zhang (Author), Li Zhang (Author), Yongjun Sun (Author), Yinghua Xie (Author), Shaomei Wu (Author), Lei Liu (Author), Zibin Gao (Author)
• Format: Book
• Published: Elsevier, 2012-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The aim of this research was to evaluate doxorubicin (DOX)-loaded zein in situ gels, a new drug delivery system in which a liquid state drug can be transformed into semi-solid after intratumoral injection. In vitro release of DOX-loaded zein was investigated and the pharmacokinetics, biodistribution...