Absence of strong strain effects in behavioral analyses of Shank3-deficient mice

• Main Authors: Elodie Drapeau (Author), Nate P. Dorr (Author), Gregory A. Elder (Author), Joseph D. Buxbaum (Author)
• Format: Bog
• Udgivet: The Company of Biologists, 2014-06-01T00:00:00Z.
• Fag: article
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Haploinsufficiency of SHANK3, caused by chromosomal abnormalities or mutations that disrupt one copy of the gene, leads to a neurodevelopmental syndrome called Phelan-McDermid syndrome, symptoms of which can include absent or delayed speech, intellectual disability, neurological changes and autism s...