Embryonic Stem Cell-Derived Cardiomyocyte Heterogeneity and the Isolation of Immature and Committed Cells for Cardiac Remodeling and Regeneration

• Main Authors: Kenneth R. Boheler (Author), Robert N. Joodi (Author), Hui Qiao (Author), Ondrej Juhasz (Author), Amanda L. Urick (Author), Sandra L. Chuppa (Author), Rebekah L. Gundry (Author), Robert P. Wersto (Author), Rong Zhou (Author)
• Format: Book
• Published: Hindawi Limited, 2011-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pluripotent stem cells represent one promising source for cell replacement therapy in heart, but differentiating embryonic stem cell-derived cardiomyocytes (ESC-CMs) are highly heterogeneous and show a variety of maturation states. In this study, we employed an ESC clonal line that contains a cardia...