Expression and function of macrophage migration inhibitory factor (MIF) in melioidosis.

• Main Authors: W Joost Wiersinga (Author), Thierry Calandra (Author), Liesbeth M Kager (Author), Gerritje J W van der Windt (Author), Thierry Roger (Author), Didier le Roy (Author), Sandrine Florquin (Author), Sharon J Peacock (Author), Fred C G J Sweep (Author), Tom van der Poll (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2010-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Macrophage migration inhibitory factor (MIF) has emerged as a pivotal mediator of innate immunity and has been shown to be an important effector molecule in severe sepsis. Melioidosis, caused by Burkholderia pseudomallei, is an important cause of community-acquired sepsis in Southeast-Asia. We aimed...