Antihyperalgesic Properties of Honokiol in Inflammatory Pain Models by Targeting of NF-κB and Nrf2 Signaling

• Main Authors: Sidra Khalid (Author), Muhammad Z. Ullah (Author), Ashraf U. Khan (Author), Ruqayya Afridi (Author), Hina Rasheed (Author), Adnan Khan (Author), Hussain Ali (Author), Yeong S. Kim (Author), Salman Khan (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The present study investigates the possible anti-nociceptive effect of intraperitoneal (i.p.) honokiol: a phenolic compound originally isolated from Magnolia officinalis, in acute and chronic inflammatory pain models. Doses of 0.1, 5, and 10 mg/kg honokiol were administered in carrageenan induced pa...