Association between MTNR1B polymorphisms and obesity in African American: findings from the Jackson Heart Study

• Autori principali: Cynthia Tchio (Autore), Solomon K. Musani (Autore), Alexander Quarshie (Autore), Gianluca Tosini (Autore)
• Natura: Libro
• Pubblicazione: BMC, 2021-05-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Abstract Background Melatonin is a hormone that is secreted at night by the pineal gland. It exerts its function by binding to the MT1 and MT2 receptors, which are encoded by the MTNR1A and MTNR1B genes, respectively. Previous studies reveal that MTNR1B variants are associated with insulin secretion...