Genetically engineered Lactobacillus paracasei rescues colonic angiotensin converting enzyme 2 (ACE2) and attenuates hypertension in female Ace2 knock out rats

• Main Authors: Xue Mei (Author), Blair Mell (Author), Sachin Aryal (Author), Ishan Manandhar (Author), Ramakumar Tummala (Author), Jasenka Zubcevic (Author), Khanh Lai (Author), Tao Yang (Author), Qiuhong Li (Author), Beng San Yeoh (Author), Bina Joe (Author)
• Format: Book
• Published: Elsevier, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Engineered gut microbiota represents a new frontier in medicine, in part serving as a vehicle for the delivery of therapeutic biologics to treat a range of host conditions. The gut microbiota plays a significant role in blood pressure regulation; thus, manipulation of gut microbiota is a promising a...