Hypertension and Cardiovascular Remodelling in Rats Exposed to Continuous Light: Protection by ACE-Inhibition and Melatonin

• Main Authors: Fedor Simko (Author), Olga Pechanova (Author), Kristina Repova Bednarova (Author), Kristina Krajcirovicova (Author), Peter Celec (Author), Natalia Kamodyova (Author), Stefan Zorad (Author), Jarmila Kucharska (Author), Anna Gvozdjakova (Author), Michaela Adamcova (Author), Ludovit Paulis (Author)
• Format: Book
• Published: Hindawi Limited, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Exposure of rats to continuous light attenuates melatonin production and results in hypertension development. This study investigated whether hypertension induced by continuous light (24 hours/day) exposure induces heart and aorta remodelling and if these alterations are prevented by melatonin or an...