Differential cell type-specific function of the aryl hydrocarbon receptor and its repressor in diet-induced obesity and fibrosis

• Main Authors: Frederike J. Graelmann (Author), Fabian Gondorf (Author), Yasmin Majlesain (Author), Birte Niemann (Author), Katarina Klepac (Author), Dominic Gosejacob (Author), Marlene Gottschalk (Author), Michelle Mayer (Author), Irina Iriady (Author), Philip Hatzfeld (Author), Sophie K. Lindenberg (Author), Klaus Wunderling (Author), Christoph Thiele (Author), Zeinab Abdullah (Author), Wei He (Author), Karsten Hiller (Author), Kristian Händler (Author), Marc D. Beyer (Author), Thomas Ulas (Author), Alexander Pfeifer (Author), Charlotte Esser (Author), Heike Weighardt (Author), Irmgard Förster (Author), Laia Reverte-Salisa (Author)
• Format: Book
• Published: Elsevier, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor regulating xenobiotic responses as well as physiological metabolism. Dietary AhR ligands activate the AhR signaling axis, whereas AhR activation is negatively regulated by the AhR repressor (AhRR). While AhR-de...