A proteomic and cellular analysis of uropods in the pathogen Entamoeba histolytica.

• Main Authors: Jacques Marquay Markiewicz (Author), Sylvie Syan (Author), Chung-Chau Hon (Author), Christian Weber (Author), Daniela Faust (Author), Nancy Guillen (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2011-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Exposure of Entamoeba histolytica to specific ligands induces cell polarization via the activation of signalling pathways and cytoskeletal elements. The process leads to formation of a protruding pseudopod at the front of the cell and a retracting uropod at the rear. In the present study, we show th...