Preparation, Characterization, and In Vivo Pharmacokinetic Study of the Supercritical Fluid-Processed Liposomal Amphotericin B

• Main Authors: Chang-baek Lim (Author), Sharif Md Abuzar (Author), Pankaj Ranjan Karn (Author), Wonkyung Cho (Author), Hee Jun Park (Author), Cheong-Weon Cho (Author), Sung-Joo Hwang (Author)
• Format: Book
• Published: MDPI AG, 2019-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Here, we aimed to prepare and optimize liposomal amphotericin B (AmB) while using the supercritical fluid of carbon dioxide (SCF-CO₂) method and investigate the characteristics and pharmacokinetics of the SCF-CO₂-processed liposomal AmB. Liposomes contai...