Vasculitis in a Child With the Hyper-IgM Variant of Ataxia-Telangiectasia

• Asıl Yazarlar: Anna K. Meyer (Yazar), Mindy Banks (Yazar), Tibor Nadasdy (Yazar), Jennifer J. Clark (Yazar), Rui Zheng (Yazar), Erwin W. Gelfand (Yazar), Jordan K. Abbott (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2019-10-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

A subset of patients with Ataxia-Telangiectasia (A-T) have dramatically reduced levels of IgG, IgA, and IgE with retained or elevated IgM levels. Several reports suggest that these A-T patients with a "hyper-IgM phenotype" (HIgM) suffer more clinical immunologic consequences than other A-T...