Chaigui granule exerts anti-depressant effects by regulating the synthesis of Estradiol and the downstream of CYP19A1-E2-ERKs signaling pathway in CUMS-induced depressed rats

• Main Authors: Jun-sheng Tian (Author), Peng-fei Qin (Author), Teng Xu (Author), Yao Gao (Author), Yu-zhi Zhou (Author), Xiao-xia Gao (Author), Xue-mei Qin (Author), Yan Ren (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: There is a significant gender difference in the prevalence of depression. Recent studies have shown that estrogen plays a crucial role in depression. Therefore, studying the specific mechanism of estrogen's role in depression can provide new ideas to address the treatment of depress...