Advances in understanding the genetic basis of inherited single gene skin barrier disorders: new clues to key genes that may be involved in the pathogenesis of atopic dermatitis Avanços no entendimento da base genética de doenças hereditárias monogênicas da barreira epidérmica: novas pistas para os principais genes que podem estar envolvidos na patogênese da dermatite atópica

• Main Authors: Joey E Lai-Cheong (Author), John A. McGrath (Author)
• Format: Book
• Published: Sociedade Brasileira de Dermatologia, 2006-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Increasing knowledge of genomic DNA sequences and genetic databases has led to the characterization of the molecular basis of several inherited skin disorders. In this review we summarize some of the major recent discoveries that have been made in defining the pathogenic mutations that cause inherit...