Increased bone mass but delayed mineralization: in vivo and in vitro study for zoledronate in bone regeneration

• Main Authors: Rongchang Wang (Author), Chaowei Liu (Author), Wenwei Wei (Author), Yanjun Lin (Author), Lin Zhou (Author), Jiang Chen (Author), Dong Wu (Author)
• Format: Book
• Published: BMC, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Bisphosphonates (BPs) are widely used to inhibit excessive osteoclast activity. However, the potential to compromise bone defect healing has limited their broader application. To better understand the influence of BPs on bone regeneration, we established a bone grafting model wit...