Thermal Stability of siRNA Modulates Aptamer- conjugated siRNA Inhibition
Oligonucleotide aptamer-mediated in vivo cell targeting of small interfering RNAs (siRNAs) is emerging as a useful approach to enhance the efficacy and reduce the adverse effects resulting from siRNA-mediated genetic interference. A current main impediment in aptamer-mediated siRNA targeting is that...
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Main Authors: | Alexey Berezhnoy (Author), Randall Brenneman (Author), Marcio Bajgelman (Author), Dawn Seales (Author), Eli Gilboa (Author) |
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Format: | Book |
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Elsevier,
2012-01-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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