Single-cell profiling of mouse and primate ovaries identifies high levels of EGFR for stromal cells in ovarian aging

• Main Authors: Ye Wei (Author), Ruidi Yu (Author), Sheng Cheng (Author), Ping Zhou (Author), Shaomei Mo (Author), Chao He (Author), Chang Deng (Author), Peng Wu (Author), He Liu (Author), Canhui Cao (Author)
• Format: Book
• Published: Elsevier, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Increased ovarian fibrosis and an expanded stromal cell compartment are the main characteristics of aging ovaries. However, the molecular mechanisms and the key factor of stromal cells underlying ovarian aging remain unclear. Here, we explored single-cell transcriptomic data of ovaries from the adul...