Endothelial Notch Signaling Regulates the Function of the Retinal Pigment Epithelial Barrier via EC Angiocrine Signaling

• Main Authors: Yali Niu (Author), Yixuan Xi (Author), Yutong Jing (Author), Ziyi Zhou (Author), Xiaojia Sun (Author), Guoheng Zhang (Author), Tianhao Yuan (Author), Tianfang Chang (Author), Guorui Dou (Author)
• Format: Book
• Published: MDPI AG, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The outer blood-retina barrier (oBRB), comprises tightly connected retinal pigment epithelium (RPE) cells, Bruch's membrane, and choroid blood vessels, and is essential for retinal health and normal visual function. Disruption of the RPE barrier and its dysfunction can lead to retinal disorders...