Betulinic Acid Enhances the Viability of Random-Pattern Skin Flaps by Activating Autophagy
Random-pattern skin flap replantation is commonly used to repair skin defects during plastic and reconstructive surgery. However, flap necrosis due to ischemia and ischemia-reperfusion injury limits clinical applications. Betulinic acid, a plant-derived pentacyclic triterpene, may facilitate flap su...
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Frontiers Media S.A.,
2019-09-01T00:00:00Z.
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