Glucose-induced insulin secretion in isolated human islets: Does it truly reflect β-cell function in vivo?
Background: Diabetes always involves variable degrees of β-cell demise and malfunction leading to insufficient insulin secretion. Besides clinical investigations, many research projects used rodent islets to study various facets of β-cell pathophysiology. Their important contributions laid the found...
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Elsevier,
2021-06-01T00:00:00Z.
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