Protective effects of silymarin on methotrexate-induced damages in rat testes

• Main Authors: Turan Yaman (Author), Ahmet Uyar (Author), Mehmet Salih Kaya (Author), Ömer Faruk Keles (Author), Baris Atalay Uslu (Author), Zabit Yener (Author)
• Format: Book
• Published: Universidade de São Paulo, 2018-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract The present study aimed to investigate the protective effects of silymarin (SMN), an antioxidant, on methotrexate (MTX)-induced damage in rat testes. Thirty-two Wistar albino rats were divided into four groups (n = 8): control, MTX (20 mg/kg, i.p. on days 1 and 5), SMN (200 mg/kg, orally),...