Efficacy of Phenotype-vs. Genotype-Guided Therapy Based on Clarithromycin Resistance for Helicobacter pylori Infection in Children

• Main Authors: Yan Feng (Author), Wenhui Hu (Author), Yuhuan Wang (Author), Junping Lu (Author), Ye Zhang (Author), Zifei Tang (Author), Shijian Miao (Author), Ying Zhou (Author), Ying Huang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BackgroundClarithromycin resistance reduces the eradication rate of Helicobacter pylori (H. pylori). Cultures with susceptibility testing and molecular determination of genotypes are recommended to guide-tailored therapy.MethodsWe retrospectively enrolled patients aged 6 and 18 years with H. pylori...