Automated pipeline for nerve fiber selection and g-ratio calculation in optical microscopy: exploring staining protocol variations

• Autores principales: Bart R. Thomson (Autor), Louise Françoise Martin (Autor), Paul L. Schmidle (Autor), Hannah Schlierbach (Autor), Anne Schänzer (Autor), Henning Richter (Autor)
• Formato: Libro
• Publicado: Frontiers Media S.A., 2023-11-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

G-ratio is crucial for understanding the nervous system's health and function as it measures the relative myelin thickness around an axon. However, manual measurement is biased and variable, emphasizing the need for an automated and standardized technique. Although deep learning holds promise,...