Microbial Antigen-Presenting Extracellular Vesicles Derived from Genetically Modified Tumor Cells Promote Antitumor Activity of Dendritic Cells

• Asıl Yazarlar: Tomoko Ito (Yazar), Kikuya Sugiura (Yazar), Aya Hasegawa (Yazar), Wakana Ouchi (Yazar), Takayuki Yoshimoto (Yazar), Izuru Mizoguchi (Yazar), Toshio Inaba (Yazar), Katsuyuki Hamada (Yazar), Masazumi Eriguchi (Yazar), Yoshiyuki Koyama (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2021-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Tumor-derived extracellular vesicles (EVs), as tumor vaccines, carry tumor-associated antigens (TAAs), and were expected to transfer TAAs to antigen-presenting cells. However, treatment with tumor-derived EVs exhibited no obvious antitumor effect on the established tumors, likely due to their immuno...