Optimization of a lentivirus-mediated gene therapy targeting HIV-1 RNA to eliminate HIV-1-infected cells

Persistence of HIV-1 in cellular reservoirs results in lifelong infection, with cure achieved only in rare cases through ablation of marrow-derived cells. We report on optimization of an approach that could potentially be aimed at eliminating these reservoirs, hijacking the HIV-1 alternative splicin...

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Main Authors: Amanda B. Buckingham (Author), Sophia Ho (Author), Finlay Knops-Mckim (Author), Carin K. Ingemarsdotter (Author), Andrew M.L. Lever (Author)
Format: Book
Published: Elsevier, 2024-12-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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