Optimization of a lentivirus-mediated gene therapy targeting HIV-1 RNA to eliminate HIV-1-infected cells
Persistence of HIV-1 in cellular reservoirs results in lifelong infection, with cure achieved only in rare cases through ablation of marrow-derived cells. We report on optimization of an approach that could potentially be aimed at eliminating these reservoirs, hijacking the HIV-1 alternative splicin...
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Main Authors: | , , , , |
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Format: | Book |
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Elsevier,
2024-12-01T00:00:00Z.
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Internet
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A1234.567 |
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Copy 1 | Available |