Optimization of a lentivirus-mediated gene therapy targeting HIV-1 RNA to eliminate HIV-1-infected cells
Persistence of HIV-1 in cellular reservoirs results in lifelong infection, with cure achieved only in rare cases through ablation of marrow-derived cells. We report on optimization of an approach that could potentially be aimed at eliminating these reservoirs, hijacking the HIV-1 alternative splicin...
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| Main Authors: | , , , , |
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| Format: | Book |
| Published: |
Elsevier,
2024-12-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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