False-negative result in molecular diagnosis of SARS-CoV-2 in samples with amplification inhibitors

• Main Authors: Marcelo Fruehwirth (Author), Açucena V. Rivas (Author), Andressa F. R. Fitz (Author), Aline Cristiane C. A. Batista (Author), Cleypson Vinicius Silveira (Author), Robson M. Delai (Author)
• Format: Book
• Published: Sociedade Brasileira de Patologia Clínica, 2020-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ABSTRACT Introduction: Although reverse transcription-polymerase chain reaction (rRT-PCR) is the gold standard method for detecting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), some factors, such as the presence of amplification inhibitors, lead to false-negative results. Objective:...