Joint modeling of monocyte HLA‐DR expression trajectories predicts 28‐day mortality in severe SARS‐CoV‐2 patients

• Main Authors: Gaelle Baudemont (Author), Coralie Tardivon (Author), Guillaume Monneret (Author), Martin Cour (Author), Thomas Rimmelé (Author), Lorna Garnier (Author), Hodane Yonis (Author), Jean‐Christophe Richard (Author), Remy Coudereau (Author), Morgane Gossez (Author), Florent Wallet (Author), Marie‐Charlotte Delignette (Author), Frederic Dailler (Author), Marielle Buisson (Author), Anne‐Claire Lukaszewicz (Author), Laurent Argaud (Author), Cédric Laouenan (Author), Julie Bertrand (Author), Fabienne Venet (Author), for the RICO study group (Author)
• Format: Book
• Published: Wiley, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract The recent SarsCov2 pandemic has disrupted healthcare system notably impacting intensive care units (ICU). In severe cases, the immune system is dysregulated, associating signs of hyperinflammation and immunosuppression. In the present work, we investigated, using a joint modeling approach,...