Single-cell transcriptome reveals Staphylococcus aureus modulating fibroblast differentiation in the bone-implant interface

• Główni autorzy: Jinlong Yu (Autor), Boyong Wang (Autor), Feiyang Zhang (Autor), Zun Ren (Autor), Feng Jiang (Autor), Musha Hamushan (Autor), Mingzhang Li (Autor), Geyong Guo (Autor), Hao Shen (Autor)
• Format: Książka
• Wydane: BMC, 2023-03-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Abstract Background This study aimed to delineate the cell heterogeneity in the bone-implant interface and investigate the fibroblast responses to implant-associated S. aureus infection. Methods Single-cell RNA sequencing of human periprosthetic tissues from patients with periprosthetic joint infect...