Single-cell transcriptome reveals Staphylococcus aureus modulating fibroblast differentiation in the bone-implant interface

• Main Authors: Jinlong Yu (Author), Boyong Wang (Author), Feiyang Zhang (Author), Zun Ren (Author), Feng Jiang (Author), Musha Hamushan (Author), Mingzhang Li (Author), Geyong Guo (Author), Hao Shen (Author)
• Format: Book
• Published: BMC, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background This study aimed to delineate the cell heterogeneity in the bone-implant interface and investigate the fibroblast responses to implant-associated S. aureus infection. Methods Single-cell RNA sequencing of human periprosthetic tissues from patients with periprosthetic joint infect...