4-Methylesculetin ameliorates LPS-induced depression-like behavior through the inhibition of NLRP3 inflammasome

• Main Authors: Khushboo Choudhary (Author), Surendra Rajit Prasad (Author), Kiran Bharat Lokhande (Author), Krishna Murti (Author), Sanjiv Singh (Author), Velayutham Ravichandiran (Author), Nitesh Kumar (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The pathophysiology of depression is heavily dependent on inflammation. Evidence suggests that the etiology of depression is linked with NLRP3 inflammasome-induced inflammation. Therefore, blocking the activated NLRP3 inflammasome may be beneficial for treating depression. Due to the limitations of...