Novel Role for miR-1290 in Host Species Specificity of Influenza A Virus

• Main Authors: Sheng-Yu Huang (Author), Chih-Heng Huang (Author), Chi-Jene Chen (Author), Ting-Wen Chen (Author), Chun-Yuan Lin (Author), Yueh-Te Lin (Author), Shu-Ming Kuo (Author), Chung-Guei Huang (Author), Li-Ang Lee (Author), Yi-Hsiang Chen (Author), Mei-Feng Chen (Author), Rei-Lin Kuo (Author), Shin-Ru Shih (Author)
• Format: Book
• Published: Elsevier, 2019-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The role of microRNA (miRNA) in influenza A virus (IAV) host species specificity is not well understood as yet. Here, we show that a host miRNA, miR-1290, is induced through the extracellular signal-regulated kinase (ERK) pathway upon IAV infection and is associated with increased viral titers in hu...