3-Chloro-N'-(2-hydroxybenzylidene) benzohydrazide: An LSD1-Selective Inhibitor and Iron-Chelating Agent for Anticancer Therapy

• Главные авторы: Federica Sarno (Автор), Chiara Papulino (Автор), Gianluigi Franci (Автор), Jeanette H. Andersen (Автор), Bastien Cautain (Автор), Colombina Melardo (Автор), Lucia Altucci (Автор), Angela Nebbioso (Автор)
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• Опубликовано: Frontiers Media S.A., 2018-09-01T00:00:00Z.
• Предметы: article
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Despite the discovery and development of novel therapies, cancer is still a leading cause of death worldwide. In order to grow, tumor cells require large quantities of nutrients involved in metabolic processes, and an increase in iron levels is known to contribute to cancer proliferation. Iron plays...