Comparing the Effect of Piperine and Ilepcimide on the Pharmacokinetics of Curcumin in SD Rats

• Main Authors: Peijian Wang (Author), Hui Li (Author), Zhexuan Lin (Author), Hongjun Luo (Author), Wenhong Luo (Author)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2021-10-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

The poor bioavailability and rapid metabolism of curcumin (CUR) restrict its clinical application. Piperine (PIP), which was extracted from natural compounds, can increase the plasma concentration of curcumin in humanidad. As an artificial synthetic piperine analog, silepcimide (ILE) has significant...